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  • What is collagen?
    The term "collagen" refers to any one of more that 28 types of polymeric glycoproteins that form elongated fibers. Collagen is commonly found in extracellular matrices.
  • Where does the AMStent(r) collagen come from?
    The cover on the AMStent(r) is a sheet of type III & IV collagen which is obtained from human amniotic membrance.
  • Is there a need for new stents on the market?
    Complication/reintervention rates for current metallic tracheal stents range approximately 20-40%. REFERENCES Breitenbücher A, et al. Long-term follow-up and survival after Ultraflex stent insertion in the management of complex malignant airway stenoses. Respiration. 2008;75(4):443-9. doi: 10.1159/000119053. Epub 2008 Mar 20. Chhajed PN, et al. Therapeutic bronchoscopy for malignant airway stenoses: choice of modality and survival. J Cancer Res Ther. 2010 Apr-Jun;6(2):204-9. doi: 10.4103/0973-1482.65250. Han X, et al. Individualized airway-covered stent implantation therapy for thoracogastric airway fistula after esophagectomy. Surg Endosc. 2017 Apr;31(4):1713-8. doi: 10.1007/s00464-016-5162-9. Epub 2016 Aug 12. Lemaire A, et al. Outcomes of tracheobronchial stents in patients with malignant airway disease. Ann Thorac Surg. 2005 Aug;80(2):434-7; discussion 437-8. Marchese R, et al. Fully covered self-expandable metal stent in tracheobronchial disorders: clinical experience. Respiration. 2015;89(1):49-56. doi: 10.1159/000368614. Epub 2015 Jan 15. McGrath EE, et al. The insertion of self expanding metal stents with flexible bronchoscopy under sedation for malignant tracheobronchial stenosis: a single-center retrospective analysis. Arch Bronconeumol. 2012 Feb;48(2):43-8. doi: 10.1016/j.arbres.2011.09.008. Epub 2011 Dec 2. Miyazawa T, et al. Implantation of ultraflex nitinol stents in malignant tracheobronchial stenosis. CHEST. 2000;69(2):398-401. Nasir BS, et al. Palliation of Concomitant Tracheobronchial and Esophageal Disease Using a Combined Airway and Esophageal Approach. Ann Thorac Surg. 2016 Aug;102(2):400-6. doi: 10.1016/j.athoracsur.2016.03.021. Epub 2016 May 5. Razi SS, et al. Timely airway stenting improves survival in patients with malignant central airway obstruction. Ann Thorac Surg. 2010 Oct;90(4):1088-93. doi: 10.1016/j.athoracsur.2010.06.093. Saad CP, et al. Self-expandable metallic airway stents and flexible bronchoscopy: long-term outcomes analysis. Chest. 2003 Nov;124(5):1993-9
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